Find a Doctor

Find a Researcher

Jasdeep Sabharwal, M.D., Ph.D.

Assistant Chief of Service
Assistant Professor of Ophthalmology

Male

Research Interests

Intraocular pressure fluctuation; Glaucoma Progression; machine learning; visual field testing ...read more

Locations

Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
Baltimore, MD 21224 map

Phone: 410-550-3000

The Johns Hopkins Hospital

600 N. Wolfe Street
Baltimore, MD 21287 map

Phone: 410-955-5650 | Fax: 410-614-8496

Background

Jasdeep Sabharwal, M.D., Ph.D., is an assistant chief of service and assistant professor of ophthalmology at the Wilmer Eye Institute, Johns Hopkins Medicine location in East Baltimore and at Johns Hopkins Bayview Medical Center. He specializes in caring for routine and complex glaucoma using medical, laser, and surgical treatment, and also performs cataract surgery.

Dr. Sabharwal completed his bachelor's degree in molecular and cell biology and neurobiology at the University of California, Berkeley, before earning his medical doctorate and Ph.D. in neuroscience at Baylor College of Medicine. He came to Wilmer to pursue his residency and glaucoma fellowship.

His Ph.D. work focused on studying retinal ganglion cells, which are the cells that are lost in glaucoma. He identified early changes in cellular function prior to cell death. This work helped develop Dr. Sabharwal's interest in ophthalmology and focus on applying quantitative methods to studying eye disease.

Titles

Assistant Chief of Service
Assistant Professor of Ophthalmology

Departments / Divisions

Ophthalmology - Glaucoma

Education

Degrees

MD; Baylor College of Medicine (2018)

Residencies

Ophthalmology; Johns Hopkins University School of Medicine (2022)

Research & Publications

Research Summary

Dr. Sabharwal's research focuses on identifying the factors driving intraocular pressure fluctuations and determining the role of fluctuations in glaucoma worsening. This work can help determine which subset of patients need more frequent visits or early interventions for glaucoma. Newer devices to continuously monitor eye pressure or to provide sustained release of eye drops have significant promis, but significant research needs to be done before they can be used in routine clinical practice.

Selected Publications

View all on PubMed

Sabharwal J*, Hou K, Herbert P, Bradley C, Johnson CA, Wall M, Ramulu PY, Unberath M, Yohannan J. A deep learning model incorporating spatial and temporal information successfully detects visual field worsening using a consensus based approach. Sci Rep. 2023 Jan 19;13(1):1041. doi: 10.1038/s41598-023-28003-6. PMID: 36658309;PMCID: PMC9852268.

Tao X, Sabharwal J, Wu SM, Frankfort BJ. Intraocular Pressure Elevation Compromises Retinal Ganglion Cell Light Adaptation. Invest Ophthalmol Vis Sci. 2020 Oct 1;61(12):15. doi: 10.1167/iovs.61.12.15. PMID: 33064129; PMCID:PMC7571289.

Tao X, Sabharwal J, Seilheimer RL, Wu SM, Frankfort BJ. Mild Intraocular Pressure Elevation in Mice Reveals Distinct Retinal Ganglion Cell Functional Thresholds and Pressure-Dependent Properties. J Neurosci. 2019 Jan 8. pii:2085-18.

Sabharwal J, Seilheimer RL, Tao X, Cowan CS, Frankfort BJ, Wu SM. Elevated IOP alters the space-time profiles in the center and surround of both ON and OFF RGCs in mouse. Proc Natl Acad Sci USA. 2017; 114(33):8859-64

Cowan CS, Sabharwal J*, Seilheimer RL, Wu SM. Distinct subcomponents of mouse retinal ganglion cell receptive fields are differentially altered by light adaptation. Vision Res. 2017;131:96-105.

Sabharwal J, Seilheimer RL, Cowan CS, Wu SM. The ON Crossover Circuitry Shapes Spatiotemporal Profile in the Center and Surround of Mouse OFF Retinal Ganglion Cells. Front Neural Circuits. 2016;10:106.

Cowan CS, Sabharwal J*, Wu SM. Space-time codependence of retinal ganglion cells can be explained by novel and separable components of their receptive fields. Physiol Rep. 2016;4(17)

PubMed

Activities & Honors

Honors

2022 Mentoring for Advancement of Physician-Scientists Award, American Glaucoma Society
2022 Heed Fellow, The Heed Ophthalmic Foundation
2021 First Place, Mitchell Prize for Resident Research, annual resident research competition
2021 Morton and Myrna Goldberg Prize, an annual award for superlative care of Wilmer patients
2016 FASEB Conference Travel Award; ARVO Conference travel award
2015 NIH/NEI Ruth L. Kirschstein National Research Service Award, F30 Grant
2009 I.L. Chaikoff Memorial Award.

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Is this you? Edit Profile